Overdose and poisoning donormyl: symptoms, treatment
French drug donormyl contributes to the rapid falling asleep, increases the duration and improves the quality of sleep, while not violating phases. But it is important to follow a regimen otherwise donormyl overdose can lead to serious complications that can cause disability.
Indications for use
Donormyl has a calming and sedative effect. Active substance affects specific areas of the brain that regulate nerve excitability. The drug has been successfully used in problems falling asleep, stress and anxiety.
Due to the fact that the active substance interact with the m-cholinergic receptors, donormil does not affect the sleep phase.
Causes of overdose
Poisoning donormyl possible:
- from intentional or unintentional taking large quantities of pills, for example, when trying to settle scores with life and accidental ingestion of the medication to the child;
- with concomitant diseases of the liver and kidneys, so these patients required regimen;
- concurrent treatment with drugs that have a sedative effect, such as antidepressants, narcotic analgesics and antitussives, antihistamine medications first-generation antihypertensive medications of Central action;
- at simultaneous reception with alcohol, as alcohol increases the sedative effect of the drug;
- in a parallel appointment with m-holinoblokatorami, for example, with atropine, as it increases the likelihood of such adverse reactions as constipation and incontinence, xerostomia;
- patients in the older age group, there is an increase in the concentration of active substance in the blood and slow its rate of excretion, which can cause vertigo and reduction of the reaction rate with the risk of falling, for example, when awakening at night.
The clinical picture of intoxication
Donormyl overdose can cause serious complications and lesions of many organs.
In the case of severe intoxication in case of untimely rendering of medical aid the drug could trigger a violation of the psyche and neurology, who may even be fatal.
You need to remember that any excess doses of the drug can cause death, as each person has a threshold of sensitivity to medications are different, and therefore the amount of the drug that caused the death of the victim, will be different.
Severe poisoning donormyl will be observed after consumption of large amounts of the drug. In the annotation to the medication prescribed that overdose may provoke the deadly outcome is possible. But practice, even if you take a lot of denormal, such victims often expects long-term treatment in a mental hospital, provided a mild CNS.
If poisoning drug can cause the following symptoms:
- drowsiness by day;
- disturbance of consciousness and hallucinations;
- limb tremor and involuntary movements;
- redness of the upper body;
- heart palpitations;
- disorder of accommodation;
- dilated pupils;
- irritability, anxiety, depression;
- extreme myopathy that is often accompanied by acute renal failure.
When such symptoms should immediately consult a specialist for professional medical help immediately.
Lethal dose denormal
Sleeping pills are popular among people who have decided to retire from life. To date, not been established how much you need to take denormal, so the dosage was fatal.
According to medical statistics, there have been no cases of death the victim from taking large doses of medication. Basically all ended in severe poisoning, hospitalization in a psychiatric hospital, or a person has been disabled until the end of life.
Donormyl and alcohol
If you take Donormyl correctly, the active ingredient relieves mental activity of the brain. It slows down all the process, the result is healthy sleep. However, medication should not be consumed simultaneously with alcohol-containing beverages and medicines, depressing acting on the Central nervous system.
If the poisoning donormyl occurred on a background of reception of alcohol, it increases the risk of death of the patient. In this case, you need to be hospitalized in Toxicological office, they can stop the signs of intoxication.
Even a small dose of ethanol potentiates the sedative effect of taking denormal, which in turn leads to the development of severe adverse reactions such as convulsions and coma.
Also caution should be exercised when concurrent taking denormal with other medicines that have a depressing effect on the Central nervous system. Since this combination has been increasing sedation.
Therapy poisoning donormyl
At the first sign of intoxication should immediately call the ambulance. Treatment of an overdose of sleeping pills should only be conducted in a hospital environment, especially when itchildren, pregnant women, the elderly and immunocompromised patients.
Before arrival of physicians, if the victim is conscious, do gastric lavage is performed. For this purpose, give him water to drink and induce vomiting by pushing the tip of the tongue. It is impossible to give the victim a solution of potassium permanganate, as when the reverse passage through the esophagus, it burns. Gastric lavage is conducted that until vomit is not will be relatively clean.
Artificial do not induce vomiting if the women in the situation, young children and senior citizens. Do not try to stop vomiting, as the body excretes the remains of a drug.
Also give the victim to drink adsorbing means, such as smectite, and to prevent dehydration medicines for oral rehydration therapy. In addition, on the recommendation of the specialist can give the victim a laxative. Therapy poisoning Donormyl is the appointment of m-cholinomimetics that cropped symptoms of intoxication.
If necessary, your doctor may prescribe anticonvulsants and conduct artificial respiration. With the development of acute nephropathy shown hemodialysis and other therapies while controlling the concentration of creatine kinase.
Prevention of poisoning
Prevention of poisoning donormyl consists primarily in the observance of the regimen prescribed by your doctor. To correctly calculated the dose of medication, he should inform about all the medicines you are taking, including dietary Supplements, especially if they contain ethanol. Also inform your doctor about concomitant pathologies of the liver and kidneys.
In addition, we must note that the drug is contraindicated in:
- individual intolerance of the active and auxiliary components, and also other antihistamine medicines;
- angle-closure glaucoma;
- lactase deficiency;
- the age of 15 years.
Also, the drug should be administered with caution to patients with sudden respiratory standstill in a dream in history, because the drug increases the risk of this symptom again.
Require adjustment of dosage denormal when you assign it to persons over 65 years of age as they may not only the emergence of dizziness, but a prolongation of the half-life of the drug and thus increases the likelihood of poisoning.
Hypnotic is permissible to prescribe for pregnant women, as it has no negative effects on the fetus. But when feeding the breast he'd refuse, this is due to the fact that no data enters whether the active substance in mother's milk. If the specialist has appointed donormyl be patient, for security purposes, is to transfer the child to artificial feeding.
The drug should be stored in inaccessible to a child's place, as he may be poisoned at random its admission, therefore, it is desirable to remove the drug under the key. To hide its worth from people who are suicidal, mentally ill patients who are unable to control their actions.