Finlepsin overdose: a lethal dose and the antidote
Overdose Finlepsin often caused by prolonged adsorption of the drug in the gastrointestinal tract. Desire as quickly as possible to alleviate their condition causes a person to exceed the recommended by Dr. the number of tablets. After a day, the body develops severe intoxication accompanied by respiratory disorders. The danger of poisoning Finlepsin is the lack of comprehensive antidote and little knowledge of the active substance.
Pharmacological properties Finlepsin
Finlepsin (carbamazepine) is a pharmacological drug that is used in the treatment and prevention of epilepsy and affective disorders. The drug is produced in form of tablets with different content of active substance. In addition to the standard dose Finlepsin is available in a prolonged form. Its constituent ingredients contribute to a gradual release of the main component of the shell.
Finlepsin widely used in the treatment of alcohol and drug addiction. These patients often have seizures on stage, the usual cancellation for their body of toxic compounds. For the prevention of seizures is used a prolonged form of Finlepsin.
Overdose occurs due to the peculiarities of its pharmacokinetic properties. After getting into the stomach for several hours metabolised by liver cells with the formation of large conglomerates. Then the transformed molecules of the active substance passes into the blood stream to the organs-targets for further transformation. Thus, the properties of the drug begin to manifest themselves only after a day after use of Finlepsin.
Antiepileptic medication used for the treatment of severe seizures posttraumatic or postencephalitic etiology. Also Finlepsin is used in the treatment of the following pathologies:
- trigeminal neuralgia;
- diabetes insipidus origin;
- diabetic neuropathy is complicated by severe pain;
- phantom pain;
- increase the formation of urine neurogenic etiology.
Proven efficacy of Finlepsin in eliminating sexual desire in dementia. The drug is used to prevent depression in patients who are prone to recurrence of the disease. Also a drug used for the relief of cramps and muscle tremor neurological in nature.
The main causes of overdose
The main reason for the poisoning of Finlepsin is a bad memory patients. Forgetting to take another in the course of treatment the pill, the man decides to catch up and drink just two. Exactly one day he developed all the symptoms of an overdose until the occurrence of hallucinations.
You cannot apply Finlepsin people with severe liver disease in the anamnesis. Capacity not able to process the base material and it becomes deposited in the tissues, exerting a toxic effect.
Poisoning Finlepsin develops when there is a history of such diseases.
- Systemic diseases.
- Inhibition of hematopoiesis.
- Adenoma of the prostate.
- Disruption of the urinary system.
- Insufficient production of hormones by the adrenal cortex or the thyroid gland.
- Elevated intraocular pressure.
Finlepsin is contraindicated in people who are sensitive to the active substance. Symptoms of overdose increased side effects Finlepsin:
- dizziness, loss of coordination, headaches, drowsiness;
- trembling of the eyeball, impaired speech, nervous tics, tremor of the upper and lower extremities;
- emotional instability, unmotivated aggression, nervous excitability;
- allergic reactions: swelling of tissues, rashes, redness of the skin;
- violations of intestinal motility, pancreatitis;
- the appearance of blood in urine, urination disorders;
- sweating, cold sweats, chills, fever.
To avoid the effects of an overdose, patients should not combine Finlepsin and alcohol. Ethyl alcohol is considered a depressant, and the properties of the drug to eliminate this negative condition. Alcoholic drinks contribute to the development of body extra adrenaline, camaudio heartbeat. Dramatically increased blood pressure – the main cause of hypertensive crisis, ending with the death of a person.
If the doctor prescribed a course of treatment with Finlepsin, the patient periodically to take biochemical analyses. According to their results it is possible to monitor the concentration of the active substance in the bloodstream. This is necessary to prevent excessive accumulation of the drug in the body.
Women planning a pregnancy, you should contact your gynecologist for a consultation. The doctor will recommend additionally take folic acid, which reduces the possibility of side effects of Finlepsin. The drug imposes some restrictions on management of vehicles. Better not to drive until full recovery.
Accidental or deliberate overdose Finlepsin can lead to excess accumulation in the tissues of unstable and toxic metabolites of the active substance. They are able to increase the frequency and severity of side effects. Symptoms of overdose increase when taking Finlepsin prolonged action.
The elderly and the elderly doctors do not recommend taking the medication with a gradual release of the main compound. Because of age changes, people forget that they already took the pills. Extra dose can cause poisoning through 24-30 hours after ingestion.
Excess Finlepsin causing pronounced neurological and cardiovascular disorders. Slow absorption of the drug in the tissues of the body causes a gradual increase in symptoms:
- Involuntary oscillatory movements of the head, tremor of the limbs.
- Violation of the coherence of motion of the muscle with preservation of the tendon and muscle reflexes.
- Fatigue, drowsiness, anxiety.
A distinctive feature of overdose is the stagnation of food inside the gastrointestinal tract. Reduced peristalsis, develop constipation, vomiting, flatulence and heartburn. The victim from Finlepsin diagnosed epigastric pain, bloating due to excess gas formation.
Poisoning Finlepsin can provoke an epileptic seizure. Cramps and discharge foam at the mouth occurs in people who have not previously suffered from epilepsy.
Gradually spreading through the body, the drug reduces the functional activity of the heart, capillaries, arteries and veins. The pathological condition is expressed by such symptoms:
- violation of intraventricular conduction.
The urinary system reacts to an overdose of the reduction of the volume discharge of urine. Urine becomes dark, foul odor.
Increased concentration of Finlepsin causes visual and auditory hallucinations, loss of coordination in space, and fainting. Suppressed respiratory function, increases the likelihood of the victim swelling of lung tissue and brain. In the absence of medical assistance, the person falls into a deep coma, and then die.
Treatment and first aid
After the appearance of the first signs of poisoning, you must call the doctor. Only a doctor can assess the condition of the victim, to prevent further spread of the poison in the body. Before the arrival of ambulance crews need to clear the stomach from the remnants of toxic compounds:
- To cook slightly pink solution of potassium permanganate and give drink to the victim.
- Should help poisoned induce vomiting by pressure of the handle of his spoon on the tongue.
- To empty the stomach prior to discharge from the stomach of pure water.
Unabsorbed Finlepsin can be neutralized by administration of activated charcoal or other adsorbents and chelators. To reassure the patient and reduce the absorption of toxic substances will help strong sweet tea.
If a person has hallucinations and unsteadiness of gait, it is necessary to put and cover. In this state, he can hurt himself or the people around him.
Increased intake Finlepsin serves as a signal for immediate hospitalization of the victim. The hospital will be held detoxification therapy. Supportive treatment based on symptoms, control over the work of all vital systems.